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    The iPLEDGE program requires that women taking isotretinoin undergo frequent pregnancy tests and commit to using two (2) forms of birth control in order to prevent themselves from getting pregnant 15 Due to the severity of the side effects, pregnancy prevention is absolutely critical
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    Dermatologists, in general, have a goal dosage in mind when treating patients with isotretinoin, and this dosage is weight-based and chosen such that most patients who fall in this range experience a prolonged "remission" of their acne Most patients, on ideal dosing at about 1 mg kg, reach this range after 5-6 months of treatment Some patients, depending upon tolerability, may need a
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