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  • Dorothy (Dori) Schafer, Ph. D. - Associate Professor — Schafer Lab
    I started my own lab at UMass Medical School in 2015 where we are continuing our work to understand how microglia modulate neural circuits in health and disease
  • Dorothy P. Schafer - Wikipedia
    Dorothy P "Dori" Schafer is an assistant professor in the department of neurobiology at University of Massachusetts Medical School Her research focuses on the role of microglia in the development of synapses and brain circuits as well as the maintenance of synaptic plasticity
  • Dorothy Schafer | Profiles RNS
    She was hired in 2015 as a tenure-track Assistant Professor in the Department of Neurobiology at The University of Massachusetts Chan Medical School She is currently an Associate Professor with tenure in the Department of Neurogiology
  • 突触修剪领域大bug！科学家发现脂褐素自发荧光影响评估小 . . .
    2023年11月3日马萨诸塞大学医学院Dorothy P Schafer研究团队在Nature Communications杂志上发表文章揭示了组织样本中存在年龄相关脂褐素的自发荧光，作为混淆因素干扰研究小胶质细胞吞噬作用，并开发出性价比高的LED灯光漂白装置消除上述自发荧光。 研究人员发现在未进行荧光染色的3月龄小鼠体感皮层、听觉和视觉皮层区域488nm、561nm、631nm激光波长可引起点状脂褐素自发荧光，但在405nm波长不存在。 通过标记小胶质细胞和溶酶体发现，约23 6%的自发荧光位于小胶质细胞内，其中绝大多数位于溶酶体中。 进一步检测不同时期（出生后第5天到24月龄多个时间段）脂褐素自发荧光，发现随着年龄的增加，脂褐素自发荧光在小胶质细胞中的聚集增多。
  • 【突触修剪新进展】Cell:科学家揭示发育期小胶质细胞限制星 . . .
    2025年9月15日马萨诸塞大学医学院Dorothy P Schafer团队在Cell杂志发表文章揭示发育期胡须剥夺刺激后小胶质细胞限制星形胶质细胞吞噬突触的分子机制。 突触修剪是一个清除过多突触的发育过程，促进神经回路成熟。
  • 《Cell》：小胶质细胞-星形胶质细胞Wnt信号调节发育期突触清除
    2025年9月15日，马萨诸塞大学医学院Dorothy P Schafer团队，在国际知名期刊Cell（IF：45 5）发表了题为“ Microglia-astrocyte crosstalk regulates synapse remodeling via Wnt signaling ”的研究性论文。
  • Dorothy P. Schafer – Cure Alzheimers Fund
    Dr Dorothy (Dori) Schafer is a leader in the field studying microglia and neural-immune interactions within neural circuits She received her bachelor’s degree in Neuroscience from Mount Holyoke College in 2001 and her Ph D from the University of Connecticut Health Center in 2008
  • ‪Dorothy Schafer‬ - ‪Google Scholar‬
    Ultrastructural analysis of the dynactin complex: an actin-related protein is a component of a filament that resembles F-actin Control of actin assembly at filament ends DA Schafer, MD Welch,
  • Dorothy P. Schafer | ScienceDirect
    Read articles by Dorothy P Schafer on ScienceDirect, the world's leading source for scientific, technical, and medical research
  • Dorothy P. Schafers research works | University of Massachusetts Chan . . .
    We show that glial circadian translatomes are highly cell-type-specific and exhibit profound, context-dependent reprogramming in response to amyloid pathology or aging





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