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  • Optimizing photoswitchable MEK - PMC
    Finally, we implement our optimized psMEK to deliver high-amplitude pulses of ERK activity in the early zebrafish embryo, revealing duration-dependent features of ERK sensing that are beyond the dynamic range of the original psMEK
  • Addgene: pLL3. 7m-psMEK2
    Plasmid pLL3 7m-psMEK2 from Dr Michael Lin's lab contains the insert psMEK2 and is published in Science 2017 Feb 24;355 (6327):836-842 doi: 10 1126 science aah3605 This plasmid is available through Addgene
  • Optimizing photoswitchable MEK - PNAS
    Finally, we implement our optimized psMEK to deliver high-amplitude pulses of ERK activity in the early zebrafish embryo, revealing duration-dependent features of ERK sensing that are beyond the dynamic range of the original psMEK
  • Optimizing photoswitchable MEK | Request PDF - ResearchGate
    Of note, S Y Shvartsman's laboratory recently optimized a photoswitchable MEK device (psMEK) to manipulate the Ras MAPK signaling using microscopy and Dronpa-based photo-dimerizable protein
  • Optimizing photoswitchable MEK - PubMed
    A recently developed photoswitchable mitogen-activated protein kinase kinase 1 (MEK1) enzyme (psMEK) short-circuits the highly conserved Extracellular Signal-Regulated Kinase (ERK)-signaling cascade at the most proximal step of effector kinase activation
  • Optimizing photoswitchable MEK. | Department of Molecular Biology
    A recently developed photoswitchable mitogen-activated protein kinase kinase 1 (MEK1) enzyme (psMEK) short-circuits the highly conserved Extracellular Signal-Regulated Kinase (ERK)-signaling cascade at the most proximal step of effector kinase activation
  • Optimizing photoswitchable MEK - Princeton University
    A recently developed photoswitchable mitogen-activated protein kinase kinase 1 (MEK1) enzyme (psMEK) short-circuits the highly conserved Extracellular Signal-Regulated Kinase (ERK)-signaling cascade at the most proximal step of effector kinase activation
  • Optimizing photoswitchable MEK - PNAS
    A recently developed photoswitchable mito-gen-activated protein kinase kinase 1 (MEK1) enzyme (psMEK) short-circuits the highly conserved Extracellular Signal-Regulated Ki-nase (ERK)-signaling cascade at the most proximal step of effector kinase activation
  • Optimizing photoswitchable MEK - preview related info | Mendeley
    A recently developed photoswitchable mitogen-activated protein kinase kinase 1 (MEK1) enzyme (psMEK) short-circuits the highly conserved Extracellular Signal-Regulated Kinase (ERK)-signaling cascade at the most proximal step of effector kinase activation





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